The adrenals and anaesthetic hyperglycaemia

The Adrenals

The adrenals, although discovered as early as 1564, were not known to have any function until the classical work of Addison in 1855. Since then, however, these glands have been the object of intensive research and the mass of literature collected up to date is simply overwhelming. In the present volume, the author has made a successful attempt to analyse the great accumulation of literature, to...

Epinephrin Content of Adrenals

In a study, mainly in cats, of the epinephrin discharge caused by electrical stimulation of the splanchnic nerves' we were led to consider the question whether the amount of epinephrin liberated by a given strength and duration of stimulation is related to the store of epinephrin already present in the adrenals, or is independent of that store. Desiring to compare the amount liberated in animal...

Hyperglycaemia and pulmonary infection.

Pathophysiological stress from acute illness causes metabolic disturbance, including altered hepatic glucose metabolism, increased peripheral insulin resistance and hyperglycaemia. Acute hyperglycaemia is associated with increased morbidity and mortality in patients in intensive care units and patients with acute respiratory disease. The present review will consider mechanisms underlying this a...

Hyperglycaemia and cancer risk

A recent Swedish prospective study on hyperglycaemia and cancer risk (1) showed an association with total cancer risk in women, and in women and men combined, for several cancer sites. The cancer incidence was compared with both fasting glucose and glucose 2 h after a 75 g glucose load. For women the relative total cancer risks for the top versus bottom quartiles were in the range of 1.3, i.e. ...

The role of lymphoid tissue and the adrenals in immunity.